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Medical Evidence-based Study for Ionic Radiation Exposure and Biomarkers of Health Effects

  • Publication Date:2021-09-08

At present, more than one hundred documents have been studied, and a comparative analysis of occupational disasters, regulations and policies in various countries and the current situation in our country has been carried out; two biological detection methods have been established, and 100 blood samples and questionnaires have been completed for 100 people exposed to ionizing radiation. Samples were received and two kinds of biodetection analysis were completed simultaneously; the establishment of the database requires inter-departmental contact and cross-filing, and the debugging is very time-consuming. Currently, the cross-filing of the exposure dose file of the Atomic Energy Council and the labor insurance database is completed. A database of ionizing radiation workers is established, and breast cancer registration files is concatenated to complete the analysis of breast cancer incidence in the exposed group. Important achievements include: 1. Completed analysis of the differences between our country’s ionizing radiation occupational disease identification and worker protection related policies and measures and major advanced countries, and specific recommendations for improvement were put forward; 2. Confirmation that the double middle section analysis method and γ-H2AX biological indicators are more suitable as an indicator of acute or short-term exposure; as for long-term low-dose occupational exposure, it is recommended to conduct human peripheral blood analysis to explore changes in the ratio of CD4/CD8; 3. The incidence of breast cancer in the ionizing radiation exposure group is higher than that of our entire country, and the age of first diagnosis is also lower than that of our entire country.

 

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Production flow chart for chromosome variability analysis slide

  • Source:Division of Occupational Hazards Assessment
  • Last updated:111-08-18
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