Bisphenal A (BPA) has been demonstrated to be both estrogenic and anti-androgenic, leading to a decrease in sperm production in humans and abnormal development of puberty in experimental animals. It may also increase carcinogenic risk, prevalence of cardiovascular diseases and diabetes in humans. As the production and consumption of BPA is growing dramatically around the world, more and more workers expose to BPA in workplace. Given the potential adverse effects of BPA on human health, it is necessary to assess the occupational exposure levels of workers and establish exposure limits to protect them. The purposes of this study are to determine the ambient BPA levels for workers in PVC film manufacturing industry and to evaluate the workers’ health risk.

Four plants were chosen as sampling sites, and 120 workers were invited to participate in the study. A structured questionnaire was distributed to collect demographic and exposure data. All workers were divided into BPA-exposure group and control group, containing 103 and 17 workers respectively. Air samples were collected by using 3-piece filter cassettes, which loaded glass-fiber fibers. BPA were measured by means of HPLC with fluorescence detector. The results showed that the possibility of exposing BPA occupationally could be excluded in PVC film plants (B, C, and D) in this study. Nevertheless, we also found that the workers in plant A exposed high level of BPA. The mean concentration in operation area was 52.81±138.80 μg/m³, with concentrations ranging from0.01 to 652.02 μg/m³, while the levels of other areas were N.D.-1.78 μg/m³. Furthermore, the BPA concentrations in plant A were also much higher than those in previous studies. We recommend that occupational permissible exposure limit and effective prevention measures should be established to protect the health of workers.